1. In Customize for headers add more fields especially 'Product'.
2. When editing a bug, have the comments history at the bottom.
3. Search within search results.
4. When clicking remove, allow the Y key to confirm. (Minor, I know)
5. Change Font/Size
6. +- for CC line is awkward. Easier to just type in names.
7. When changing status to Fixed automatically select Resolved.
8. In drop down boxes, have a richer UI more like MS Office font selection. In other words, if I type 'Jo' it would automatically select 'John Smith'
9. Attachments in the Edit Window. Drag/Drop & Cut/paste like email attachments.
10. On Edit Bug, put the bug number in the title. This will make it show up inthe Start menu on Windows.